Once-A-Day Male Contraceptive Pill Successful In First Clinical Trials

Male contraceptive pill on the horizon

That's more of a personal dig considering I've literally forgotten my keys in my own front door (this week), but apparently not only has a new study shown promise that male birth control pills work, but that they are safe.

This new male contraceptive pill is a drug called dimethandrolone undecanoate, or DMAU.

The study's senior investigator, Stephanie Page, M.D., PhD, professor of medicine at the University of Washington is calling it a major step forward in the development of a once-daily "male pill". The team have overcome previous problems that assailed developers of male hormonal pills, she believes.

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But, it's not inconceivable that the nerve agent might have been used by someone other than Russian Federation , he said. Vladamir Putin has said that he will make a final decision, and that it "won't take long".

And despite having low levels of testosterone, very few subjects reported symptoms of testosterone deficiency, Page said. DMAU works by suppressing several hormones, including testosterone, required for sperm production, and the first study of 100 men found that a once daily dosage, over time, hit levels low enough to limit the amount of sperm.

The study included 100 healthy men between ages 18 and 50 years. Other forms of contraceptive for men are also in development. The groups who took DMAU experienced weight gain and had lowered levels of HDL, or "good" cholesterol, side effects that Page noted were mild. However, scientists are developing those types of male contraceptive methods, as well. The pills were taken for 28 days once daily with food. Unlike other forms of oral testosterone, which classically are cleared from the body quickly, this compound contains a specific long-chain fatty acid that slows this clearance making it a flawless "once-a-day" pill. It found that an experimental drug is both safe and effective. The results of a recent study were presented by researchers at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, on Sunday. It's 99 per cent effective when taken perfectly, Planned Parenthood wrote, but added that it's hard to do this. All participants also passed safety tests, Science Daily reported.

As it was acknowledged that further studies are needed to gauge whether the new contraceptive for men can truly be effective in actual use, the researchers hope to determine in the future whether the drug affects sperm count for a span of three months. One of the major downsides of this medical innovation - and something which had been an issue before 1960 as well - is that women are often expected to deal with birth control by themselves. Men who want a reversible form of contraception have said in surveys that they would prefer a pill to injections or gels, which are also being developed.

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